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HIF1A His Recombinant Protein

Product Sizes
10 µg
£528.00
32-3958-10UG
About this Product
SKU:
32-3958
Additional Names:
Hypoxia-inducible factor 1 alpha||HIF-1 alpha||HIF1 alpha||ARNT-interacting protein||Member of PAS protein 1||Basic-helix-loop-helix-PAS protein MOP1||HIF1A||MOP1||HIF1||PASD8||HIF-1A.
Extra Details:
Source : Escherichia Coli. HIF1A Recombinant Human produced in E.Coli is a single; non-glycosylated polypeptide chain containing 231 amino acids (576-785 a.a.) and having a molecular mass of 25.1 kDa. The HIF1A is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. HIF1A has a role as a master transcriptional monitor of the adaptive response to hypoxia. Under hypoxic conditions HIF1A activates the transcription of over 40 genes; including; erythropoietin; glucose transporters; glycolytic enzymes; vascular endothelial growth factor; and genes whose protein products increase oxygen release or facilitate metabolic adaptation to hypoxia. HIF1A functions as an essential role in embryonic vascularization; tumor angiogenesis and pathophysiology of ischemic disease.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg