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HAX1 Recombinant Protein

Product Sizes
10 µg
£528.00
32-3937-10UG
About this Product
SKU:
32-3937
Additional Names:
HCLS1-associated protein X-1||HS1-associating protein X-1||HS1-binding protein 1||HAX-1||HSP1BP-1||HAX1||HS1BP1.
Extra Details:
Source : E.coli. HAX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 299 amino acids (1-279) and having a molecular mass of 33.7kDa. HAX1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HAX1 associates with hematopoietic cell-specific Lyn substrate 1; which is a substrate of Src family tyrosine kinases. HAX1 also interacts with the product of the polycystic kidney disease 2 gene; mutations in which are associated with autosomal-dominant polycystic kidney disease; and with the F-actin-binding protein; cortactin. It was earlier thought HAX1 is mainly localized to the mitochondria; however; recent studies indicate it to be localized in the cell body. Mutations in the HAX1 gene result in autosomal recessive severe congenital neutropenia; aka Kostmann disease.
Purification:
Greater than 80% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg