HAUS1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-3936-10UG
About this Product
- SKU:
- 32-3936
- Additional Names:
- HAUS augmin-like complex subunit 1||Coiled-coil domain-containing protein 5||Enhancer of invasion-cluster||HEI-C||HAUS1||CCDC5||HEIC||HsT1461.
- Extra Details:
- Source : Escherichia Coli. HAUS1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 302 amino acids (1-278 a.a) and having a molecular mass of 34.4kDa.HAUS1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HAUS augmin-like complex subunit 1 (HAUS1) is 1 of 8 subunits of the 390kDa human augmin complex/ HAUS complex. The augmin complex is a microtubule-binding complex required in microtubule generation within the mitotic spindle and is imperative to mitotic spindle compilation. HAUS1 contributes to mitotic spindle assembly; maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. HAUS1 is broadly expressed; especially in the pancreas; kidney; skeletal muscle; liver and heart. However it is weakly expressed in the lung; brain and placenta. HAUS1-depleted cells hold functional cell cycle checkpoints; but the depletion reduces the G2/M cell cycle compartment and stimulates apoptosis. The HAUS1 protein level remains constant through the cell cycle.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
