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H3F3A Recombinant Protein

Product Sizes
20 µg
£528.00
32-3935-20UG
About this Product
SKU:
32-3935
Additional Names:
RP11-396C23.1||H3.3A||H3F3||Histone H3.3||H3 Histone||Family 3A.
Extra Details:
Source : Escherichia Coli. H3F3A Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 159 amino acids (1-136 a.a) and having a molecular mass of 17.7kDa.H3F3A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. H3F3A is a member of the histone H3 family. Histones are basic nuclear proteins which are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Histones play a significant role in transcription regulation; DNA repair; DNA replication and chromosomal stability. DNA accessibility is regulated by a complex set of post-translational modifications of histones; also called histone code; and nucleosome remodeling. Two molecules of each of the four core histones H2A; H2B; H3; and H4 form an octamer; around that approximately 146 bp of DNA is wrapped in repeating units; called nucleosomes. The linker histone; H1; interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg