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GOPC Recombinant Protein

Product Sizes
25 µg
£528.00
32-3910-25UG
About this Product
SKU:
32-3910
Additional Names:
CAL||dJ94G16.2||FIG||GOPC1||PIST||Golgi-associated PDZ and coiled-coil motif-containing protein||PDZ protein interacting specifically with TC10||CFTR-associated ligand||Fused in glioblastoma||GOPC.
Extra Details:
Source : Escherichia Coli. GOPC Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 198 amino acids (278-454 a.a.) and having a molecular mass of 21.5 kDa. The GOPC is fused to a 20 amino acid His Tag and purified by conventional chromatography. GOPC is a PDZ domain-containing Golgi protein which binds the extreme C terminus of proteins in a sequence-specific manner. GOPC participates in intracellular protein trafficking and degradation. GOPC regulates CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC regulates the intracellular trafficking of the ADR1B receptor. GOPC takes part in autophagy. GOPC over expression results in CFTR intracellular retention and degradation in the lysosomes.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
GOPC although stable 4[o]C for 4 weeks; should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg