GNB3 Recombinant Protein
Product Sizes
20 µg
£528.00
32-3902-20UG
About this Product
- SKU:
- 32-3902
- Additional Names:
- Transducin Beta Chain 3||G Protein||Beta-3 Subunit||GTP-Binding Regulatory Protein Beta-3 Chain||Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3||Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-3||Hypertension Associat
- Extra Details:
- Source : Escherichia Coli. GNB3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 363 amino acids (1-340 a.a) and having a molecular mass of 39.6kDa.GNB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. GNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit; as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition; this polymorphism is also linked with the occurrence of the splice variant GNB3-s; which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3; however they have not been fully described. Among the diseases associated with GNB3 are syncope; and aortic coarctation.
- Purification:
- Greater than 80.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
