GCA Recombinant Protein
Product Sizes
10 µg
£528.00
32-3866-10UG
About this Product
- SKU:
- 32-3866
- Additional Names:
- Grancalcin EF-hand calcium binding protein||GCL||Grancalcin penta-EF-hand protein.
- Extra Details:
- Source : Escherichia Coli. GCA produced in E.Coli is a single; non-glycosylated polypeptide chain containing 237 amino acids (1-217.a.) and having a molecular mass of 26.1kDa. GCA is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Grancalcin is calcium-binding protein which is particularly abundant in human neutrophils. GCA is a member of the penta EF-hand (PEF) subfamily of EF-hand proteins; who also comprises calpain; sorcin; peflin; and ALG-2. GCA undergoes essential conformational changes upon binding of calcium; which subsequently exposes hydrophobic amino acid residues; that direct the protein to hydrophobic surfaces. GCA cooperates with L-plastin; a protein known to have actin bundling activity; which suggests that GCA has a part in the regulation of neutrophils adhesion.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
