FAM84B Recombinant Protein
Product Sizes
20 µg
£528.00
32-3812-20UG
About this Product
- SKU:
- 32-3812
- Additional Names:
- FAM84B||Family with Sequence Similarity 84 Member B||BCMP101||Breast Cancer Membrane-Associated Protein 101||Neurological/Sensory 2||Breast Cancer Membrane Protein 101||NSE2||Protein FAM84B||Protein NSE2.
- Extra Details:
- Source : Escherichia Coli. FAM84B Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 333 amino acids (1-310) and having a molecular mass of 36.9kDa.FAM84B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Family with Sequence Similarity 84; Member B (FAM84B) coprecipitated with a downstream effector of RAS; CRAF. Binding of FAM83B with CRAF interrupted CRAF/14-3-3 interactions and increased CRAF membrane localization; causing elevated MAPK and mammalian target of rapamycin (mTOR) signaling. FAM84B is an oncogene and possibly represents a new target for therapeutic intervention.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
