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EXOSC8 Recombinant Protein

Product Sizes
10 µg
£528.00
32-3776-10UG
About this Product
SKU:
32-3776
Additional Names:
Exosome Component 8||EXOSC8||OIP2||RRP43||CBP-Interacting Protein 3||Opa Interacting Protein 2||Opa-Interacting Protein 2||Ribosomal RNA-Processing Protein 43||OIP-2||p9||CIP3||EAP2||Rrp43p||bA421P11.3||Exosome Complex Component RRP43||Exosome Comple
Extra Details:
Source : Escherichia Coli. EXOSC8 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 299 amino acids (1-276) and having a molecular mass of 32.4 kDa.EXOSC8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Exosome component 8 and transcription factor 4 (EXOSC8) is a part of the exosome complex. In the cytoplasm; the RNA exosome complex is engaged in general mRNA turnover and specifically degrades naturally unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions; and in RNA inspection pathways; preventing translation of aberrant mRNAs. EXOSC8 appears to be involved in degradation of histone mRNA. EXOSC8 attaches to ARE-containing RNAs. The EXOSC8 gene encodes a 3'-5' exoribonuclease; which specifically interacts with mRNAs containing AU-rich elements. The EXOSC8 protein is part of the exosome complex; which is significant for the degradation of many RNA species.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg