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EIF3I Recombinant Protein

Product Sizes
20 µg
£528.00
32-3733-20UG
About this Product
SKU:
32-3733
Additional Names:
Eukaryotic Translation Initiation Factor 3||Subunit I||EIF3S2; Eukaryotic Translation Initiation Factor 3||Subunit 2 Beta||36kDa||Eukaryotic Translation Initiation Factor 3 Subunit 2||TRIP-1||eIF-3-beta||EIF3 P36||TGF-Beta Receptor-Interacting Protei
Extra Details:
Source : Escherichia Coli. EIF3I Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 348 amino acids (1-325aa) and having a molecular mass of 38.9kDa.EIF3I is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Eukaryotic translation initiation factor 3; subunit I (EIF3I) is part of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is essential for numerous steps in the initiation of protein synthesis. The eIF-3 complex links with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2: GTP: methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also essential for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Among the diseases associated with EIF3I are clonorchiasis; and tonsillitis.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg