EIF2S1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-3731-10UG
About this Product
- SKU:
- 32-3731
- Additional Names:
- Eukaryotic translation initiation factor 2 subunit 1||Eukaryotic translation initiation factor 2 subunit alpha||eIF-2-alpha||EIF-2alpha||EIF-2A||EIF2||EIF-2||EIF2A||EIF-2A.
- Extra Details:
- Source : Escherichia Coli. EIF2S1 Recombinant Human produced in E.Coli is a single; non-glycosylated polypeptide chain containing 335 amino acids (1-315 a.a.) and having a molecular mass of 38.2 kDa. The EIF2S1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. EIF2S1 participates in the premature steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA which binds to a 40S ribosomal subunit; followed by mRNA binding to create a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation; the GDP bound to eIF-2 should exchange with GTP by way of a reaction catalyzed by eIF-2B.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
