EIF2B1 Recombinant Protein
Product Sizes
5 µg
£528.00
32-3730-5UG
About this Product
- SKU:
- 32-3730
- Additional Names:
- Translation initiation factor eIF-2B subunit alpha||eIF-2B GDP-GTP exchange factor subunit alpha||EIF2B1||EIF2BA||EIF2B.
- Extra Details:
- Source : Escherichia Coli. EIF2B1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 325 amino acids (1-305 a.a.) and having a molecular mass of 35.8kDa.EIF2B1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. EIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B); which is a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Phosphorylation of eIF2 inhibits GEF activity of EIF2B; an inhibition which requires the eIF2B1 subunit. Defects in eIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM); a brain disease which is characterized by head trauma and motor deterioration.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
