EDA2R Recombinant Protein
Product Sizes
20 µg
£528.00
32-3705-20UG
About this Product
- SKU:
- 32-3705
- Additional Names:
- Ectodysplasin A2 Receptor||XEDAR||TNFRSF27||EDA-A2 Receptor||X-Linked Ectodysplasin-A2 Receptor||EDAA2R||EDA-A2R||Tumor Necrosis Factor Receptor Superfamily Member 27||Tumor Necrosis Factor Receptor Superfamily Member XEDAR||EDAR2.
- Extra Details:
- Source : Escherichia Coli. EDA2R Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 161 amino acids (1-138 a.a) and having a molecular mass of 17.7kDa.EDA2R is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. EDA2R (ectodysplasin A2 receptor) mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated through binding to TRAF3 and TRAF6. In addition; Mutations in EDA give rise to a clinical syndrome characterized by loss of hair; sweat glands; and teeth. EDA2R specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily; and contains 3 cysteine-rich repeats and a single transmembrane domain however it lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. Among the diseases associated with EDA2R are ectodermal dysplasia 1; hypohidrotic; x-linked; and hypohidrotic ectodermal dysplasia.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
