DEDD Recombinant Protein
Product Sizes
10 µg
£528.00
32-3668-10UG
About this Product
- SKU:
- 32-3668
- Additional Names:
- CASP8IP1||DEDD1||DEFT||FLDED1||KE05||DEDPro1||Death effector domain-containing testicular molecule.
- Extra Details:
- Source : Escherichia Coli. DEDD Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 338 amino acids (1-318a.a) and having a molecular mass of 38.9kDa. DEDD is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Death effector domain-containing protein (DEDD) is a cytoplasmic protein. The cell death activity of DEDD relates to its nuclear localization. DEDD translocates to the nucleus during CD95-mediated apoptosis; there it localizes to nucleoli-like structures; activates caspase-6 and particularly inhibits RNA polymerase I-dependent transcription. DEDD is usually expressed in a variety of tissues; and found in the highest levels in the testis. Overexpression of DEDD was shown to induce weak apoptosis.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
