CRNN Recombinant Protein
Product Sizes
25 µg
£528.00
32-3602-25UG
About this Product
- SKU:
- 32-3602
- Additional Names:
- SEP53||DRC1||PDRC1||Cornulin||Tumor-related protein||Squamous epithelial heat shock protein 53||53 kDa squamous epithelial-induced stress protein||58 kDa heat shock protein||53 kDa putative calcium-binding protein||CRNN||C1orf10.
- Extra Details:
- Source : Escherichia Coli. CRNN Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 515 amino acids (1-495 a.a.) and having a molecular mass of 55.7 kDa. The CRNN is purified by proprietary chromatographic techniques. CRNN is part of the 'fused gene' family of proteins; which enclose N-terminus EF-hand domains and multiple tandem peptide repeats. CRNN contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. CRNN; also known as SEP53; which participates in the mucosal/epithelial immune response and epidermal differentiation. CRNN is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines; attenuates deoxycholic acid (DCA)-induced apoptotic cell death and discharge of calcium. When CRNN is over expressed in oral squamous carcinoma cell lines; it regulates negatively cell proliferation by the induction of G1 arrest.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
