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COX5B Recombinant Protein

Product Sizes
10 µg
£528.00
32-3581-10UG
About this Product
SKU:
32-3581
Additional Names:
Cytochrome c oxidase subunit 5B||mitochondrial precursor||COXVB||COX5B||Mitochondrial||Cytochrome c oxidase polypeptide Vb.
Extra Details:
Source : Escherichia Coli. COX5B Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 121 amino acids (32-129a.a) and having a molecular mass of 13kDa. COX5B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cytochrome c oxidase subunit VB (COX5B) is the terminal enzyme of the mitochondrial respiratory chain. COX5B is a multi-subunit enzyme complex which couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. There are two isoforms of COX5:COX5a and COX5b. Transcription of COX5A (the aerobic isoform) is up-regulated as the rate of cellular respiration increases; when oxygen levels within the cell are high. However; when oxygen levels are low; COX5B (the hypoxic isoform) transcription increases and functions to maximize the turnover rate of the COX apoenzyme.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg