CLPS Recombinant Protein
Product Sizes
20 µg
£528.00
32-3552-20UG
About this Product
- SKU:
- 32-3552
- Additional Names:
- Colipase Pancreatic||Pancreatic Colipase Preproprotein||Colipase||CLPS.
- Extra Details:
- Source : Escherichia Coli. CLPS Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 118 amino acids (18-112) and having a molecular mass of 12.5 kDa.CLPS is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Colipase (CLPS) is a protein co-enzyme essential for optimal enzyme activity of pancreatic lipase. CLPS is secreted by the pancreas as an inactive form; procolipase; which is then activated in the intestinal lumen by trypsin. CLPS prevents the inhibitory effect of bile salts on the lipase-catalyzed intraduodenal hydrolysis of dietary long-chain triglycerides. CLPS allows lipase to anchor noncovalently to the surface of lipid micelles; counteracting the destabilizing influence of intestinal bile salts. CLPS binds to the C-terminal; non-catalytic domain of lipase; thus stabilizing an active conformation and significantly increasing the whole hydrophobic binding site.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
