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CFB (26-259) Recombinant Protein

Product Sizes
20 µg
£528.00
32-3514-20UG
About this Product
SKU:
32-3514
Additional Names:
Complement factor B (EC:3.4.21.47)||C3/C5 convertase||Glycine-rich beta glycoprotein||GBG||PBF2||Properdin factor B||Complement factor B Ba fragment||Complement factor B Bb fragment||CFB||Complement Factor B||BFD||AHUS4||BF||BFD||CFAB||FB||FBI12||H2-
Extra Details:
Source : Escherichia Coli. CFB (26-259) Human Recombinant produced in E. coli is. a single polypeptide chain containing 257 amino acids and having a molecular mass of 28.4kDa. CFB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Complement Factor B; also known as CFB; encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also; Bb is involved in the proliferation of preactivated B lymphocytes; while Ba inhibits their proliferation.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg