CCM2 Recombinant Protein
Product Sizes
10 µg
£528.00
32-3429-10UG
About this Product
- SKU:
- 32-3429
- Additional Names:
- Cerebral Cavernous Malformation 2||C7orf22||malcavernin||Cerebral Cavernous Malformations 2 Protein||Chromosome 7 Open Reading Frame 22||OSM||MGC4067.
- Extra Details:
- Source : Escherichia Coli. CCM2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 311 amino acids (66-353 a.a) and having a molecular mass of 34.3kDa.CCM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cerebral Cavernous Malformation 2; also known as CCM2 is a piece of the CCM signaling pathway which is a vital regulator of heart and vessel formation as well as integrity. CCM2 performs through the stabilization of endothelial cell junctions. In addition; CCM2 functions as a scaffold protein for MAP2K3-MAP3K3 signaling. CCM2 plays a key role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock. Mutations in CCM2 result in cerebral cavernous malformations. Multiple transcript variants encoding dissimilar isoforms have been discovered for CCM2.
- Purification:
- "Greater than 90.0% as determined by SDS-PAGE."
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
