C12ORF5 Recombinant Protein
Product Sizes
10 µg
£528.00
32-3363-10UG
About this Product
- SKU:
- 32-3363
- Additional Names:
- Probable fructose-2;6-bisphosphatase TIGAR||TP53-induced glycolysis and apoptosis regulator||TIGAR||C12orf5.
- Extra Details:
- Source : Escherichia Coli. C12ORF5 Human Recombinant fused with a 24 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 294 amino acids (1-270 a.a.) and having a molecular mass of 32.6kDa. The C12ORF5 is purified by proprietary chromatographic techniques. TP53-induced glycolysis and apoptosis regulator (TIGAR or C12ORF5); is a 270 amino acid protein induced by the p53 tumor suppressor pathway that functions to protect against oxidative stress. C12ORF5 specifically functions to block glycolysis; leading the pathway to the pentose phosphate shunt and decreasing the intracellular concentration of reactive oxygen species. Therefore; it is thought that C12ORF5 may act to modulate the apoptotic response to p53; thus allowing cells to survive mild or transient stresses.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- C12ORF5 should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
