BIRC7 (1-280) Recombinant Protein
Product Sizes
10 µg
£528.00
32-3337-10UG
About this Product
- SKU:
- 32-3337
- Additional Names:
- Baculoviral IAP repeat-containing protein 7||KIAP||MLIAP||RNF50||ML-IAP||LIVIN||Kidney inhibitor of apoptosis protein||Melanoma inhibitor of apoptosis protein||RING finger protein 50||BIRC7.
- Extra Details:
- Source : Escherichia Coli. BIRC7 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 304 amino acids (1-280 a.a.) and having a molecular mass of 33.4kDa.BIRC7 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BIRC7 is a part of the inhibitor of apoptosis protein (IAP) family and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is necessary for inhibitory activity & cooperates with caspases; while the RING finger domain sometimes increases anti-apoptotic activity but doesn't inhibit apoptosis by itself. 2 transcript variants encoding diverse isoforms have been found for this gene. The 2 isoforms have dissimilar antiapoptotic characteristics; with isoform a protecting cells from apoptosis induced by staurosporine and isoform b defending cells from apoptosis induced by etoposide. BIRC7 has direct contact with several caspases together with caspase-3; caspase-7; & caspase -9. BIRC7 inhibits the activation of caspase-9 induced by Apaf-1; cytochrome c; and dATP.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
