BCL10 Recombinant Protein
Product Sizes
5 µg
£528.00
32-3301-5UG
About this Product
- SKU:
- 32-3301
- Additional Names:
- B-cell CLL/lymphoma 10||B-cell lymphoma/leukemia 10||Mammalian CARD-containing adapter molecule E10||CARD-containing molecule enhancing NF-kappa-B||CED-3/ICH-1 prodomain homologous E10-like regulator||CARD-containing apoptotic signaling protein
- Extra Details:
- Source : E.coli. BCL10 Human Recombinant produced in E. coli is a single polypeptide chain containing 257 amino acids (1-233) and having a molecular mass of 28.8kDa (molecular weight on SDS-PAGE will appear higher).BCL10 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BCL10 holds a caspase recruitment domain (CARD); and is known as an inducer of apoptosis and as NF-kappaB activator. BCL10 cooperates with other CARD domain containing proteins such as CARD9; 10; 11 and 14; which operates as upstream regulators in NF-kappaB signaling. BCL10 is known to create a complex with MALT1; a protein encoded by another gene and is translocated in MALT lymphoma. MALT1 and BCL10 protein synergize the activation of NF-kappaB; and the deregulation of either of them facilitates the same pathogenetic process which leads to the malignancy.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
