ARPP19 Recombinant Protein
Product Sizes
20 µg
£528.00
32-3249-20UG
About this Product
- SKU:
- 32-3249
- Additional Names:
- CAMP-Regulated Phosphoprotein 19kDa||ARPP-19||ARPP16||Endosulfine Alpha-Like||ARPP-16||ENSAL||CAMP-Regulated Phosphoprotein 19||Cyclic AMP Phosphoprotein 19 KD||ARPP19.
- Extra Details:
- Source : Escherichia Coli. ARPP19 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 135 amino acids (1-112 a.a) and having a molecular mass of 14.7kDa.ARPP19 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. cAMP-regulated phosphoprotein 19 (ARPP19) is protein phosphatase inhibitor which specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis; ARPP19 specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity; leading to inactivation of PP2A; a vital condition to maintain cyclin-B1-CDK1 activity high during M phase. ARPP19 protein may indirectly boost GAP-43 expression. The 19 kDa cAMP-regulated phosphoprotein has a role in regulating mitosis by obstructing protein phosphatase-2A.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
