ARFIP2 Recombinant Protein
Product Sizes
20 µg
£528.00
32-3229-20UG
About this Product
- SKU:
- 32-3229
- Additional Names:
- ADP-ribosylation factor interacting protein 2||partner of RAC1 (arfaptin 2)||Partner of RAC1||Protein POR1||arfaptin-2||POR1.
- Extra Details:
- Source : E.coli. ARFIP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 364 amino acids (1-341) and having a molecular mass of 40.2 kDa.ARFIP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Arfaptin 2 (ARFIP2) is a Rac1 binding protein essential for Rac-mediated actin polymerization and the succeeding formation of membrane ruffles and lamellipodia. ARFIP2 is a putative target protein of ADP-ribosylation factor. ARFIP2 is also involved in membrane ruffling. ARFIP2 expression is increased at sites of neurodegeneration. In addition; ARFIP2 interacts with the ADP ribosylation factor ARF6; a GTPase which associates with the plasma membrane and intracellular endosome vesicles; in a GTP dependent mode. Furthermore; Arfaptin 2 controls the aggregation of mutant Huntingtin protein by weakening proteasome function.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
