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Bovine Aprotinin Native Protein

Product Sizes
250 mg
£705.00
32-3218-250MG
About this Product
SKU:
32-3218
Additional Names:
Pancreatic trypsin inhibitor||Basic protease inhibitor||BPI||BPTI||Aprotinin||AP.
Extra Details:
Source : Bovine Lung. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7} arranged in a single polypeptide chain; cross-linked by three disulfide bridges and having a molecular mass of 6512. Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin; kallikrein; plasmin and trypsin. Aprotinin is present in blood and in most tissues; with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets; aprotinin reduces glycoprotein loss (e.g.; GpIb; GpIIb/IIIa); while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g.; CD11b).
Purification:
Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized Aprotinin although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Aprotinin should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg