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STAT1 Recombinant Protein

Product Sizes
10 µg
£528.00
32-3114-10UG
About this Product
SKU:
32-3114
Additional Names:
Signal transducer and activator of transcription 1-alpha/beta||Transcription factor ISGF-3 components p91/p84||STAT1||ISGF-3||STAT91||DKFZp686B04100.
Extra Details:
Source : Escherichia Coli. STAT1 Recombinant Human produced in E.Coli is a single; non-glycosylated polypeptide chain containing 732 amino acids (1-712 a.a.) and having a molecular mass of 85.2 kDa. The STAT1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. STAT1 is a member of the Signal Transducers and Activators of Transcriptionfamily of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type Ior type IIinterferons. In response to IFN-stimulation; STAT1 forms homodimers or heterodimers with STAT3that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element; in response to either IFN- or IFN-stimulation; STAT1 forms a heterodimer with STAT2that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case; binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes).
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg