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PRKAB2 Recombinant Protein

Product Sizes
20 µg
£528.00
32-3100-20UG
About this Product
SKU:
32-3100
Additional Names:
5'-AMP-activated protein kinase subunit beta-2||AMPK subunit beta-2.
Extra Details:
Source : E.coli. PRKAB2 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 296 amino acids (1-272) and having a molecular mass of 32.8kDa. PRKAB2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer contains an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK is a significant energy-sensing enzyme that supervises cellular energy status. AMPK is activated as a reply to cellular metabolic stresses; therefore phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR); vital enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 is a positive regulator of AMPK activity and highly expressed in skeletal muscle.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg