PRKAB1 Recombinant Protein
Product Sizes
5 µg
£528.00
32-3099-5UG
About this Product
- SKU:
- 32-3099
- Additional Names:
- AMPK||HAMPKb||5'-AMP-activated protein kinase subunit beta-1||AMPK subunit beta-1||AMPKb;PRKAB1.
- Extra Details:
- Source : E.coli. PRKAB1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 293 amino acids (1-270 a.a.) and having a molecular mass of 32.8 kDa. The PRKAB1 is fused to a 23 amino acid His Tag at N-Terminus and purified by proprietary chromatographic techniques. 5'-AMP-activated protein kinase subunit beta-1 (PRKAB1) hinders protein; carbohydrate and lipid biosynthesis; in addition to cell growth and proliferation. AMPK is a heterotrimer comprised of an alpha catalytic subunit; and non-catalytic beta and gamma subunits. AMPK acts via direct phosphorylation of metabolic enzymes; and longer-term effects by phosphorylation of transcription regulators. PRKAB1 is a regulator of cellular polarity by remodeling the actin cytoskeleton; most likely by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex compiles; through its C-terminus that joins alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1; PRKAG2 or PRKAG3).
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
