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p16-INK4a Recombinant Protein

Product Sizes
20 µg
£528.00
32-3066-20UG
About this Product
SKU:
32-3066
Additional Names:
Cyclin-dependent kinase 4 inhibitor A||CDK4I||p16-INK4||p16-INK4a||p16INK4A||CDKN-2A||CDKN2||Multiple tumor suppressor 1||MTS1||CMM2||MLM||TP16||p16(INK4)||p19.
Extra Details:
Source : Escherichia Coli. CDKN2A Human Recombinant produced in E.Coli; it's a single non-glycosylated polypeptide chain containing 156 amino acids; approximately 16.5 kDa.CDKN2A is purified by proprietary chromatographic techniques. Cyclin-dependent kinase inhibitors (CDKIs) are proteins that bind to and inhibit the activity of CDKs. Two major classes of CDK inhibitors have been identified. The p16 family (p15; p16; p18 and p19) binds to and inhibits the activities of CDK4 and CDK6. The p21 family (p21; p27; p28 and p57) can bind to broad range of CDK-cyclin complexes and inhibit their activities. CDKIs are capable of suppressing growth; and several lines of evidence strongly suggest that at least some CDKIs may be tumor suppressor proteins.
Purification:
Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized Cyclin-dependent kinase although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Cyclin-dependent kinase should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg