MVK Recombinant Protein
Product Sizes
20 µg
£528.00
32-3061-20UG
About this Product
- SKU:
- 32-3061
- Additional Names:
- Mevalonate Kinase (Mevalonic Aciduria)||LH Receptor MRNA-Binding Protein||LRBP||Mevalonate Kinase 1||MK||MVLK||EC 2.7.1.36.
- Extra Details:
- Source : Escherichia Coli. MVK Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 419 amino acids (1-396) and having a molecular mass of 44.8kDa.The MVK is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. MVK is a member of the GHMP kinase family. Mevalonate is a vital mediator; and MVK an important early enzyme; in isoprenoid and sterol synthesis. MVK deficiency can result in gene mutation associated with Mevalonic aciduria; an illness which causes psychomotor retardation; failure to thrive hepatosplenomegaly; anemia and frequent febrile crises. Mutations in this gene also cause hyperimmunoglobulinaemia D and sporadic fever syndrome; in which the person suffers from recurrent episodes of fever related with lymphadenopathy; skin rash; gastrointestinal dismay and arthralgia.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
