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MEK1 Recombinant Protein

Product Sizes
5 µg
£528.00
32-3058-5UG
About this Product
SKU:
32-3058
Additional Names:
MEK1||MKK1||MAPKK1||MAP2K1||Dual specificity mitogen-activated protein kinase kinase 1||MAP kinase kinase 1||EC 2.7.12.2||ERK activator kinase 1||MAPK/ERK kinase 1||PRKMK1.
Extra Details:
Source : Sf9 Insect Cells. MAP2K1 active Human Recombinant produced in Sf9 cells is a glycosylated; polypeptide chain containing amino acids 2-393 having a molecular mass of 47 kDa. MAP2K1 is fused to a polyhistidine tag and is purified by proprietary chromatographic techniques. MAP2K1 is a member of the dual specificity protein kinase family; which plays a role as a mitogen-activated protein (MAP) kinase kinase. MAP kinases; are recognized as extracellular signal-regulated kinases (ERKs); that act as an integration position for multiple biochemical signals. MEK1 is located upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As a key player of MAP kinase signal transduction pathway; MEK1 is involved in many cellular processes such as proliferation; differentiation; transcription regulation and development. MAP2K1 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a thr-glu-tyr sequence located in map kinases. MEK1 activates erk1 and erk2 map kinases.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 1-2 weeks. Store frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg