HK-1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-3029-10UG
About this Product
- SKU:
- 32-3029
- Additional Names:
- Hexokinase-1||EC 2.7.1.1||Hexokinase type I||HK I||Brain form hexokinase||HK1-ta||HK1-tb||HXK1||HK1.
- Extra Details:
- Source : Escherichia Coli. HK1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain fused to 20 amino acids His tag at the N-terminal encoding the sequence of 937 amino acids and having a molecular mass of 104.6 kDa.HXK1 is purified by proprietary chromatographic techniques. Hexokinases phosphorylate glucose to produce glucose-6-phosphate; thus committing glucose to the glycolytic pathway. Hexokinase1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of HXK1 results in five transcript variants which encode different isoforms; some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described; but due to the presence of several stop codons; it is not thought to encode a protein.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
