CDKN1B Recombinant Protein
Product Sizes
20 µg
£528.00
32-2967-20UG
About this Product
- SKU:
- 32-2967
- Additional Names:
- Cyclin-dependent kinase inhibitor 1B||Cyclin-dependent kinase inhibitor p27||p27Kip1||CDKN1B||KIP1||MEN4||CDKN4||MEN1B.
- Extra Details:
- Source : Escherichia Coli. CDKN1B Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 218 amino acids (1-198 a.a.) and having a molecular mass of 24.2kDa (Molecular weight on SDS-PAGE will appear higher).CDKN1B is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a member of the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The CDKN1B protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes; and so controls the cell cycle progression at G1. CDKN1B is often referred to as a cell cycle inhibitor protein since its major function is to stop or slow down the cell division cycle. The degradation of the CDKN1B protein; which is triggered by its CDK dependent phosphorylation and ensuing ubiquitination by SCF complexes; is compulsory for the cellular transition from inactive to the proliferative state.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
