CDKN1A Recombinant Protein
Product Sizes
10 µg
£528.00
32-2966-10UG
About this Product
- SKU:
- 32-2966
- Additional Names:
- Cyclin-Dependent Kinase Inhibitor 1A (P21||Cip1)||Melanoma Differentiation Associated Protein 6||Wild-Type P53-Activated Fragment 1||CDK-Interaction Protein 1||DNA Synthesis Inhibitor||CDK-Interacting Protein 1||CDKN1||P21Cip1/Waf1||MDA6||P21CIP1||CA
- Extra Details:
- Source : Escherichia Coli. CDKN1A Human Recombinant produced in E. coli is a single polypeptide chain containing 184 amino acids (1-164) and having a molecular mass of 20.2 kDa.CDKN1A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CDKN1A holds a key part in the cellular response to DNA mutation. CDKN1A overexpression causes cell cycle to stop. When collaborating with CDK2 complexes; CDKN1A aids to prevent kinase activity and inhibits progression through G1/S. Nevertheless; CDKN1A can additionally increase assembly and activity in complexes of CDK4 or CDK6 and cyclin D. CDKN1A is a vital intermediary by which p53/TP53 facilitates its part as an inhibitor of cellular proliferation as a reaction to DNA impairment.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
