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BLK Recombinant Protein

Product Sizes
10 µg
£528.00
32-2947-10UG
About this Product
SKU:
32-2947
Additional Names:
Tyrosine-protein kinase Blk||B lymphocyte kinase||p55-Blk||BLK||MODY11||MGC10442.
Extra Details:
Source : Escherichia Coli. BLK Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 525 amino acids (1-505 a.a.) and having a molecular mass of 59.8kDa.BLK is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. B lymphoid kinase (BLK) is a 55kDa tyrosine kinase with SH3; SH2; and catalytic domains which contain consensus sequences of the Src protein tyrosine kinase family. BLK is a nonreceptor tyrosine-kinase belonging to the src family of proto-oncogenes which are typically involved in cell proliferation and differentiation. The BLK protein is expressed specifically in the B cell lineage and has a role in the signal-transduction pathway which is restricted to B lymphoid cells. In addition; BLK stimulates insulin synthesis and secretion in response to glucose and increases the expression of several pancreatic beta-cell transcription factors.
Purification:
Greater than 80.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg