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TYMS Recombinant Protein

Product Sizes
25 µg
£528.00
32-2876-25UG
About this Product
SKU:
32-2876
Additional Names:
TMS||EC 2.1.1.45||HST422||Thymidylate synthase||TSase||TS||TYMS||MGC88736.
Extra Details:
Source : Escherichia Coli. Thymidylate synthase Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 333 amino acids (1-313 a.a.) and having a molecular mass of 37.8 kDa. The Thymidylate synthase fused to a 20 amino acid His-Tag at N-Terminus and purified by proprietary chromatographic techniques. Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5;10-methylenetetrahydrofolate as a cofactor which maintains the dTMP (thymidine-5-prime monophosphate) pool vital for DNA replication and repair. Thymidylate synthase plays an important role as a cancer chemotherapeutic agent. Thymidylate synthase is the primary site of action for 5-fluorouracil; 5-fluoro-2-prime-deoxyuridine; and several folate analogs.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Thymidylate synthase although stable 4[o]C for 4 weeks; should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg