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TIMP2 HEK Recombinant Protein

Product Sizes
10 µg
£528.00
32-2853-10UG
About this Product
SKU:
32-2853
Additional Names:
TIMP metallopeptidase inhibitor 2||CSC-21K||tissue inhibitor of metalloproteinase 2||TIMP-2||metalloproteinase inhibitor 2.
Extra Details:
Source : HEK293 Cells. TIMP2 Human Recombinant produced in HEK-293 cells is a secreted protein with the sequence of Human TIMP-2 (amino acids Cys27-Pro220) and is fused to a polyhistidine tag at the C-terminus. TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases; a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases; the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently; the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors; and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized TIMP2 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution TIMP2 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg