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TIMP2 His Recombinant Protein

Product Sizes
20 µg
£528.00
32-2851-20UG
About this Product
SKU:
32-2851
Additional Names:
TIMP metallopeptidase inhibitor 2||metalloproteinase inhibitor 2||Tissue inhibitor of metalloproteinases 2||TIMP-2||CSC-21K.
Extra Details:
Source : E.coli. TIMP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 232 amino acids (27-220) and having a molecular mass of 26.1 kDa.TIMP2 is fused to a 38 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases; a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases; the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently; the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors; and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.
Purification:
Greater than 85% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg