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SERPINE1 Recombinant Protein

Product Sizes
25 µg
£528.00
32-2807-25UG
About this Product
SKU:
32-2807
Additional Names:
PAI-1||PAI1||PLANH1||SERPINE1||PAIE||PLASMINOGEN ACTIVATOR INHIBITOR||BETA-MIGRATING ENDOTHELIAL-CELL-DERIVED TYPE.
Extra Details:
Source : Escherichia Coli. SERPINE1 Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single; non-glycosylated polypeptide chain containing 400 amino acids (24-402) and having a molecular mass of 45 kDa.The SERPINE1 is purified by proprietary chromatographic techniques. Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator(tPA) and urokinase(uPA); the activators of plasminogenand hence fibrinolysis(the physiological breakdown of blood clots). It is a serine protease inhibitor(serpin) protein (SERPINE1). The other PAI; plasminogen activator inhibitor-2(PAI-2) is secreted by the placentaand only present in significant amounts during pregnancy. In addition; protease nexinacts as an inhibitor of tPA and urokinase. SERPINE1; however; is the main inhibitor of the plasminogen activators.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg