REV1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2781-20UG
About this Product
- SKU:
- 32-2781
- Additional Names:
- REV1 Polymerase (DNA Directed)||REV1L||Alpha Integrin-Binding Protein 80||Rev1-Like Terminal Deoxycytidyl Transferase||AIBP80||REV1 (Yeast Homolog)- Like||REV1 Homolog (S. Cerevisiae) ||REV1-Like (Yeast) ||DNA Repair Protein REV1||REV1 Homolog
- Extra Details:
- Source : Escherichia Coli. REV1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 227 amino acids (51-256) and having a molecular mass of 25.2kDa.REV1 is fused to a 21 amino acid His-tag at N-terminus. REV1 Polymerase (REV1) contains a BRCT domain; which is imperative in protein-protein interactions. REV1 is a deoxycytidyl transferase involved in DNA repair. REV1 assists in the 1st step in the bypass of abasic lesions by the incorporation of a nucleotide opposite the lesion. REV1 is essential for normal generation of mutations by physical and chemical agents. REV1 transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. A role for the human Rev1-like protein has been suggested as a scaffold which recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
