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PSMB8 Recombinant Protein

Product Sizes
20 µg
£528.00
32-2755-20UG
About this Product
SKU:
32-2755
Additional Names:
D6S216||D6S216E||LMP7||MGC1491||PSMB5i ||Low molecular mass protein 7 Macropain subunit C13||Multicatalytic endopeptidase complex subunit C13;Proteasome component C13||Proteasome subunit beta-5i||Really interesting new gene 10 protein.
Extra Details:
Source : Escherichia Coli. PSMB8 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 229 amino acids (73-276 a.a.) and having a molecular mass of 25.4kDa. PSMB8 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Proteasome Subunit Beta Type 8 (PSMB8) is a member of the peptidase T1B family. The proteasome is a multicatalytic proteinase complex with well-organized ring-shaped 20S core structure. Proteasomes are spread through eukaryotic cells at a high concentration. PSMB8 is mainly expressed in immature dendritic cells. vital function of a modified proteasome; the immunoproteasome; is the processing of class I MHC peptides.PSMB8 is positioned in the class II region of the MHC (main histocompatibility complex). PSMB8 plays as a significant factor of interferon gamma-induced sensitivity and in apoptosis by degradation of the apoptotic inhibitor MCL1.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg