PPP3CA Recombinant Protein
Product Sizes
5 µg
£528.00
32-2722-5UG
About this Product
- SKU:
- 32-2722
- Additional Names:
- Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform||CAM-PRP catalytic subunit||Calmodulin-dependent calcineurin A subunit alpha isoform||PPP3CA||CALNA||CAN||CALN||CCN1||CNA1||PPP2B||CALNA1.
- Extra Details:
- Source : Escherichia Coli. PPP3CA Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 534 amino acids (1-511 a.a.) and having a molecular mass of 60kDa. The PPP3CA is purified by proprietary chromatographic techniques. PPP3CA (aka Calcineurin A) is a major soluble calmodulin binding protein in the brain and a Ca2+/calmodulin dependent serine/threonine protein phosphatase; with a relatively limited substrate specificity. PPP3CA activates the T cells of the immune system and can be blocked by drugs. PPP3CA activates NFATc (a transcription factor) by dephosphorylating it. The activated NFATc is subsequently translocated into the nucleus; where it upregulates the expression of interleukin 2.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
