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PPME1 Recombinant Protein

Product Sizes
20 µg
£528.00
32-2715-20UG
About this Product
SKU:
32-2715
Additional Names:
Protein phosphatase methylesterase 1||PME-1||FLJ22226||EC 3.1.1.
Extra Details:
Source : E.coli. PPME1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 406 amino acids (1-386) and having a molecular mass of 44.4 kDa.The PPME1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. PPME1 catalyzes the demethylation and inactivation of protein phosphatase (PP2A); a multimeric phosphoserine/ threonine protein phosphatase related to growth inhibition and cell cycle arrest. PPME1 can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment can inhibit this reaction. It is conserved from yeast to human and holds a motif found in lipases having a catalytic triad activated serine as their active site nucleophile.
Purification:
Greater than 95% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg