POLB Recombinant Protein
Product Sizes
20 µg
£528.00
32-2692-20UG
About this Product
- SKU:
- 32-2692
- Additional Names:
- DNA polymerase beta||POLB.
- Extra Details:
- Source : Escherichia Coli. POLB Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 355 amino acids (1-335 a.a) and having a molecular mass of 40.3kDa.POLB is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. DNA polymerase beta (POLB) is a member of the DNA polymerase type-X family. In eukaryotic cells; POLB performs base excision repair necessary for DNA maintenance; replication; recombination; and drug resistance. POLB has 2 separate domains; the larger is the polymerase domain itself; whereas a small basic N-terminal domain contains an AP lyase activity which excises the abasic sugar-phosphate residue at the strand break. POLB fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells. POLB overexpression; as seen in some human tumors; could convene an increase in spontaneous mutagenesis.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
