PNPO Recombinant Protein
Product Sizes
20 µg
£528.00
32-2690-20UG
About this Product
- SKU:
- 32-2690
- Additional Names:
- Pyridoxine-5'-phosphate oxidase||Pyridoxamine-phosphate oxidase||PNPO||PDXPO||FLJ10535.
- Extra Details:
- Source : Escherichia Coli. PNPO Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 226 amino acids (57-261 a.a.) and having a molecular mass of 25.9kDa. The PNPO is purified by proprietary chromatographic techniques. Pyridoxine-5'-phosphate oxidase (PNPO) is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function; and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts.Vitamin B6 is an essential co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in the PNPO gene result in PNPO deficiency; a form of neonatal epileptic encephalopathy.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- HSD17B14 should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
