PLA2G7 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2683-20UG
About this Product
- SKU:
- 32-2683
- Additional Names:
- Platelet-activating factor acetylhydrolase||PAF acetylhydrolase||PAF 2-acylhydrolase||LDL-associated phospholipase A2||LDL-PLA(2)||2-acetyl-1-alkylglycerophosphocholine esterase||1-alkyl-2-acetylglycerophosphocholine esterase||PLA2G7||PAFAH||LP-PLA2;
- Extra Details:
- Source : Escherichia Coli. PLA2G7 Human Recombinant produced in E.Coli is single; a non-glycosylated; Polypeptide chain containing 420 amino acids fragment (22-441) having a total molecular mass of 52.29kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The PLA2G7 is purified by proprietary chromatographic techniques. PLA2G7 is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. The PLA2G7 enzyme is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood; PLA2G7 goes mainly with LDL and less than 20% is coupled with HDL. PLA2G7 is implicated in the development of atherosclerosis and is also a marker for cardiac disease. PLA2G7 might have a major physiologic effect in the presence of inflammatory bodily responses.PLA2G7 alters the action of PAF (platelet-activating factor) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PLA2G7 has specificity for substrates with a short residue at the sn-2 position. PLA2G7 is inactive against long-chain phospholipids.PLA2G7 gene defects are the source of platelet-activating factor acetylhydrolase deficiency; which is a trait that is present in 27% of the Japanese population.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
