PDE6D Recombinant Protein
Product Sizes
20 µg
£528.00
32-2649-20UG
About this Product
- SKU:
- 32-2649
- Additional Names:
- Retinal rod rhodopsin-sensitive cGMP 3'';5''-cyclic phosphodiesterase subunit delta|| Phosphodiesterase 6D cGMP-Specific Rod Delta||GMP-PDE delta||Protein p17||PDE6D||PDED.
- Extra Details:
- Source : Escherichia Coli. PDE6D produced in E.Coli is a single; non-glycosylated polypeptide chain containing 158 amino acids (1-150 a.a.) and having a molecular mass of 18.4kDa. PDE6D is fused to an 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques. Human PDE6D was initially identified as a fourth subunit of rod-specific cGMP phosphodiesterase; PDE6. PDE6D is an Oligomer composed of two catalytic chains (alpha and beta); an inhibitory chain (gamma) and the delta chain. PDE6D interacts with RPGR; ARL2 and ARL3. The catalytically active PDE6 is a heterodimer ( alpha Beta) that is controlled by two inhibitory Gamma subunits. Since PDE6D does not change the catalytic properties of PDE alpha Beta; its function is still unanswered. PDE6D is expressed specifically in the retina.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
