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NEIL1 Recombinant Protein

Product Sizes
5 µg
£528.00
32-2602-5UG
About this Product
SKU:
32-2602
Additional Names:
Endonuclease 8-like 1||DNA glycosylase/AP lyase Neil1||DNA-(apurinic or apyrimidinic site) lyase Neil1||Endonuclease VIII-like 1||FPG1||Nei homolog 1||NEH1||Nei-like protein 1||NEIL1||NEI1||hFPG1.
Extra Details:
Source : Escherichia Coli. NEIL1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 410 amino acids (1-390) and having a molecular mass of 45.8kDa.NEIL1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NEIL1 is a member of a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. NEIL1 participates in the DNA repair pathway by initiating base excision repair by removing damaged bases; primarily oxidized pyrimidines.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg