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NANA Recombinant Protein

Product Sizes
20 µg
£528.00
32-2580-20UG
About this Product
SKU:
32-2580
Additional Names:
N-acetylneuraminate lyase||N-acetylneuraminate pyruvate-lyase||N-acetylneuraminic acid aldolase||NALase||Sialate lyase||Sialic acid aldolase||Sialic acid lyase||nanA||npl||b3225||JW3194.
Extra Details:
Source : Escherichia Coli. NANA produced in E.Coli is a single; non-glycosylated polypeptide chain containing 317 amino acids (1-297 a.a.) and having a molecular mass of 34.7kDa.NANA is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. N-acetylneuraminate lyase (NanA) is a member of a family of lyases; specifically the oxo-acid-lyases; which cleave carbon-carbon bonds. NanA catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetyl-D-mannosamine. NanA is inhibited by reduction with NaBH4 in the presence of the substrate; which indicates that it belongs to the Schiff-base-forming Class I aldolases. NanA is strongly inhibited by Cu2+ ions; p-chloromercuribenzoate and N-bromosuccinimide; it is also inhibited competitively by the reaction product; pyruvate; and its structurally related compounds; dihydroxyacetone and DL-glyceraldehyde.
Purification:
Greater than 95% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
NANA E.Coli Recombinant although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg