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NAE1 Recombinant Protein

Product Sizes
10 µg
£528.00
32-2579-10UG
About this Product
SKU:
32-2579
Additional Names:
NEDD8-activating enzyme E1 regulatory subunit||Amyloid beta precursor protein-binding protein 1 59 kDa||APP-BP1||Amyloid protein-binding protein 1||Proto-oncogene protein 1||NAE1||APPBP1||HPP1||ula-1||A-116A10.1.
Extra Details:
Source : Escherichia Coli. NAE1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 557 amino acids (1-534) and having a molecular mass of 62.7kDa.NAE1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NEDD8-activating enzyme E1 regulatory subunit (NAE1) is a member of the ubiquitin-activating E1 family. NAE1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties; and it is believed to have a role in the pathogenesis of Alzheimer's disease. NAE1 participates in a unique ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Furthermore; the NAE1 protein is essential for cell cycle progression through the S/M checkpoint.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg